Applications

Free-Surface Dynamics

Free-surface systems are topologically complex and almost always time-varying. The transient, high-resolution simulation accessible using M-Star CFD provides detailed insights into the sloshing, vortexing, and rocking that characterize these systems.

CFD Modeling Capabilities

M-Star CFD was built to run on millions and billions of lattice grid points. This allows you to model complex free-surface systems—including filling and draining systems—accurately and in minutes.

Latest Resources

See M-Star in action with on-demand webinars, demos and more.

Published in Chemical Engineering Communications

Modeling free surface gas transfer in agitated lab-scale bioreactors

Read how researchers at AbbVie are using M-Star CFD to examine mass transfer properties and shaker flasks, as well as the energy dissipation rates within the fluid.

webinar

Interfacial Mass Transfer in Gas-Liquid Systems

M-Star President John Thomas discusses interfacial mass transfer within the context of free-surface and sparged-gas systems. The webinar covers the physics driving mass transfer, as well as approaches for modeling these physics in industrial engineering systems. Emphasis is given to dissolved oxygen and CO2 transfer, as related to cell growth and pH control.

Case Study

How AbbVie Built Digital Twins to Understand Miscible Fluid Blending

With M-Star CFD software, AbbVie built accelerated digital twins of a physical mixing tank to predict real-time fluid mechanics with a fidelity that rivals experimental data.

Case Study

Bristol Myers Squibb Predicts Mass & Oxygen Transfer in Bioreactors

BMS used M-Star CFD to build time dependent, bubble-resolved, two-phase models to investigate the real-time blending, and mass and oxygen transfer in stirred tank bioreactors.

Case Study

How Pfizer Leveraged Digital Twins to Create a Process Scale-Up Roadmap

Pfizer built digital twins with M-Star CFD to perform lab experiments in silico, accelerating the speed of manufacturing innovation and minimizing the scope of required supporting experimental studies.

Publication

Validating Lattice Boltzmann LES for Biopharma Equipment Characterization

Boehringer Ingelheim and the Institute of Multiphase Flows use M-Star CFD to apply transient LB LES to a 3L bioreactor system and compare results to a steady RANS simulation.

Applications

Free-Surface Dynamics

CFD Modeling Capabilities

Latest Resources

See M-Star in action with on-demand webinars, demos and more.

Published in Chemical Engineering Communications

Modeling free surface gas transfer in agitated lab-scale bioreactors

webinar

Interfacial Mass Transfer in Gas-Liquid Systems

Case Study

How AbbVie Built Digital Twins to Understand Miscible Fluid Blending

Case Study

Bristol Myers Squibb Predicts Mass & Oxygen Transfer in Bioreactors

Case Study

How Pfizer Leveraged Digital Twins to Create a Process Scale-Up Roadmap

Publication

Validating Lattice Boltzmann LES for Biopharma Equipment Characterization

Get Started with M-Star