CFD Applications

What Systems Do You Need to Model?

M-Star CFD helps you rapidly and accurately model complex physics simulations across multiple applications. Explore some of our clients’ models below—or let us know what you need.

Bioreactors

M-Star CFD helps you rapidly and accurately model complex physics simulations across multiple applications. Explore some of our clients’ models below—or let us know what you need.

Agitated Tanks

Mixing processes in multi-fluid systems present more complicated competition between fluid inertia and buoyancy. M-Star CFD helps you model and predict real-time fluid mechanics with greater speed and fidelity than ever before.

Recirculation Systems

Recirculation and jet-mixing systems present competition between blend time and residence time—along with strong spatial variations in fluid velocity. As a fully transient and three-dimensional solver, M-Star CFD is ideally suited to capture these complex physics.

CFD-DEM Simulations

Particle-laden systems often require the simultaneous solution of the fluid field, particle fields, and interactions between the two phases. The GPU-based implementation of M-Star CFD makes large-scale simulations of such systems accessible and practical.

Free-Surface Dynamics

Free-surface systems are topologically complex and almost always time-varying. The transient, high-resolution simulation accessible using M-Star CFD provides detailed insights into the sloshing, vortexing, and rocking that characterize these systems.

Droplet Dispersion

Two-fluid dispersion processes are crucial to many drug product and chemical manufacturing processes. M-Star CFD uses rigorous first-principles modeling approaches for predicting droplet size distributions and dispersion physics.

HVAC & Climate Control

M-Star CFD helps engineers visualize problems and generate solutions to optimize HVAC system designs—fast, accurately, and cost-effectively—without having to install or build a physical prototype.

Behind the Physics

M-Star CFD was built to run on millions and billions of lattice grid points, so you can model almost anything accurately and in minutes. M-Star CFD applications include but are not limited to:
  • Free Surface Flows
  • Two-Fluid Stratification
  • Residence Time Distributions
  • Oxygen Transfer
  • Droplet Dispersion
  • Particle Dissolution
  • Reactions
  • Particle Size Distribution
  • Non-Spherical Particles
  • Bubbly Flows
  • Open Systems
  • Particle Breakup
  • Complex Rheology
  • Blending
  • Particle Growth
  • CFD-DEM
  • Filling/Draining
  • And Much More

Case Study

How AbbVie Built Digital Twins to Understand Miscible Fluid Blending

With M-Star CFD software, AbbVie built accelerated digital twins of a physical mixing tank to predict real-time fluid mechanics with a fidelity that rivals experimental data.

Case Study

Bristol Myers Squibb Predicts Mass & Oxygen Transfer in Bioreactors

BMS used M-Star CFD to build time dependent, bubble-resolved, two-phase models to investigate the real-time blending, and mass and oxygen transfer in stirred tank bioreactors.

Case Study

How Pfizer Leveraged Digital Twins to Create a Process Scale-Up Roadmap

Pfizer built digital twins with M-Star CFD to perform lab experiments in silico, accelerating the speed of manufacturing innovation and minimizing the scope of required supporting experimental studies.

Publication

Validating Lattice Boltzmann LES for Biopharma Equipment Characterization

Boehringer Ingelheim and the Institute of Multiphase Flows use M-Star CFD to apply transient LB LES to a 3L bioreactor system and compare results to a steady RANS simulation.

Get Started with M-Star

Contact us to speak to an M-Star and CFD expert and get a customized demonstration and free trial.